Upstream Advances Tomato Disease-Resilience Program
Upstream Biotechnology is advancing tomato-focused disease-resilience work designed to combine premium quality traits with broad-spectrum disease-resistance potential.
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Follow updates from Upstream Biotechnology as we advance SwitchBlade-enabled crop-resilience traits through validation, partnership, and commercial development.
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Upstream initiates small-plot field trials for soybean disease-resistance trait
Field validation began for Upstream's soybean disease-resistance trait, marking a key step in advancing SwitchBlade crop-resilience programs toward partner-ready data packages.
View field-validation programUpstream selected for AgLaunch365 2024 cohort
Selection for AgLaunch365 strengthened Upstream's connection to farmer-focused validation, market insight, and agricultural commercialization support.
Read moreHow plants reprogram cells to fight invaders
Plant immune responses involve sophisticated changes in gene expression, cellular defense, and resource allocation. Upstream's platform is built to translate those insights into practical crop resilience.
Explore the technologyThe science that got us here
Peer-reviewed research behind the platform.
Upstream's technology builds on decades of research in plant immunity, translational regulation, and the biological balance between defense and growth.
Biomolecular condensates in plant immunity
Huang & Dong, Cell Host & Microbe, 2025
Read paperTranslational Regulation of Plant Stress Responses: Mechanisms, Pathways, and Applications in Bioengineering
Xiang & Dong, Annual Review of Phytopathology, 2025
Read paperH₂O₂ sulfenylates CHE, linking local infection to the establishment of systemic acquired resistance
Cao et al., Science, 2024
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